KMID : 1123920050190010184
|
|
Korean Journal of Oriental Physiology and Pathology 2005 Volume.19 No. 1 p.184 ~ p.190
|
|
Effect of Germinated Seed of Rhynchosia Volubilis on Cathepsin-K in Ovariectomized Rats
|
|
Jung Ho-Long
Cha Yun-Yeop Lee Eung-Se
|
|
Abstract
|
|
|
The aim of this study is to find out what inhibition effects the Germinated Seed of Rhynchosia Volubilis(GSRV) has by its feeding period on the bone absorption in ovariectomized white rats. Close examination of the amounts of the Cathepsin-K in the rats by the groups of one, two and three-day germination periods led to the following conclusions. Feeding non-ovariectomized white rats with GSRV by the groups of one, two and three-day germination periods showed less amounts of Cathepsin-K in their proximal tibia in all the feeding periods of two, three and four weeks than in the case of control group, revealing a statistical significance. Feeding ovariectomized white rats with GSRV by the groups of one, two and three-day germination periods showed less amounts of Cathepsin-K in their proximal tibia in all the feeding periods of two, three and four weeks than in the case of the control group, revealing a statistical significance. Therefore, the Germinated Seed of Rhynchosia Volubilis(GSRV) is believed to have inhibition effects on bone resorption.
|
|
KEYWORD
|
|
Rhynchosia Volubilis, Cathepsin-K, Osteoporosis, bone resorption
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|